This webpage is intended for UK patients who have been prescribed Metoject® PEN. If you are not, please click here.

Introducing the NEW button-free Metoject® PEN

Offering the simplicity of a button-free autoinjector, purpose designed with patient-friendly features – Available from March 2024

Metoject® PEN For Dermatology

Metoject PEN® is used to treat moderate to severe psoriasis in adult patients who are candidates for systemic therapy, and severe psoriatic arthritis in adults4.

Methotrexate in Dermatology

Known as a systemic treatment, methotrexate acts on the whole body rather than targeting one area6.

Methotrexate has been used to treat psoriasis for many years3, and it works by calming down the body’s immune system, preventing it from attacking itself. This in turn helps to reduce the thickened skin in psoriasis2.

Please visit the Psoriasis Association webpage at for more psoriasis and psoriatic arthritis specific information and support.

Metoject® PEN should only be administered once per week

Support materials

Further information on how to use or administer Metoject® PEN for adults and juveniles visit the support materials page.

Reporting Side Effects

If you get any side effects, talk to your healthcare professional. This includes any possible side effects not listed in the Patient Information Leaflet contained within your Metoject® PEN carton.

You can also report side effects directly via the Yellow Card Scheme at

By reporting side effects, you can help provide more information on the safety of this medicine.

Further Information & Questions


  1. About Methotrexate. [online] Available at: Last Accessed May 2023.
  2. Common Questions about Methotrexate. [online] Available at: Last Accessed May 2023.
  3. Psoriasis Association. [online] Available at: Last Accessed May 2023.
  4. Metoject® Summary of Product Characteristics. [online] Available at: Last Accessed May 2023
  5. Methotrexate and Its Use in Rheumatoid Arthritis (RA). NRAS. [online] Available at: Last Accessed May 2023.
  6. Systemic Treatments. Psoriasis Association. [online] Available at: Last Accessed May 2023.
  7. How to Approach Your Rheumatology Consultation. [online] Available at: Last Accessed June 2023.